Detalhe da pesquisa
1.
A human blood-arachnoid barrier atlas of transporters, receptors, enzymes, and tight junction and marker proteins: Comparison with dog and pig in absolute abundance.
J Neurochem
; 161(2): 187-208, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35226354
2.
Understanding the suitability of established antibiotics for oral inhalation from a pharmacokinetic perspective: an integrated model-based investigation based on rifampicin, ciprofloxacin and tigecycline in vivo data.
J Antimicrob Chemother
; 77(11): 2922-2932, 2022 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35904005
3.
Regional Differences in the Absolute Abundance of Transporters, Receptors and Tight Junction Molecules at the Blood-Arachnoid Barrier and Blood-Spinal Cord Barrier among Cervical, Thoracic and Lumbar Spines in Dogs.
Pharm Res
; 39(7): 1393-1413, 2022 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-35488144
4.
The potent and selective RIPK2 inhibitor BI 706039 improves intestinal inflammation in the TRUC mouse model of inflammatory bowel disease.
Am J Physiol Gastrointest Liver Physiol
; 321(5): G500-G512, 2021 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34494462
5.
Discovery of tetrahydroindazoles as a novel class of potent and in vivo efficacious gamma secretase modulators.
Bioorg Med Chem
; 26(12): 3227-3241, 2018 07 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29735425
6.
Quantification of Transporter and Receptor Proteins in Dog Brain Capillaries and Choroid Plexus: Relevance for the Distribution in Brain and CSF of Selected BCRP and P-gp Substrates.
Mol Pharm
; 14(10): 3436-3447, 2017 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28880093
7.
Discovery and development of BI 1265162, an ENaC inhibitor for the treatment of cystic fibrosis.
Eur J Med Chem
; 265: 116038, 2024 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38157597
8.
Impaired regenerative capacity and senescence-associated secretory phenotype in mesenchymal stromal cells from samples of patients with aseptic joint arthroplasty loosening.
J Orthop Res
; 40(2): 513-523, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33749912
9.
Towards a Quantitative Mechanistic Understanding of Localized Pulmonary Tissue Retention-A Combined In Vivo/In Silico Approach Based on Four Model Drugs.
Pharmaceutics
; 12(5)2020 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32365674
10.
A Small-Molecule-Responsive Riboswitch Enables Conditional Induction of Viral Vector-Mediated Gene Expression in Mice.
ACS Synth Biol
; 9(6): 1292-1305, 2020 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32427483
11.
Inhibition of inducible nitric oxide synthase in respiratory diseases.
Biochem Soc Trans
; 37(Pt 4): 886-91, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19614613
12.
Montelukast exerts no acute direct effect on NO synthases.
Pulm Pharmacol Ther
; 20(5): 525-33, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-16815057
13.
Dichotomal role of TNF in experimental pulmonary edema reabsorption.
J Immunol
; 175(5): 3402-8, 2005 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16116234